
Tips for Living with a Weakened Immune System
August 1, 2025 | Rheumatic Disease

Rheumatic conditions, or autoimmune conditions, oftentimes are treated with medications that weaken a person’s immune system. Living with a weakened immune system can be challenging, but with a positive outlook and the right strategies, individuals can stay safe and live a fulfilling lifestyle. Whether undergoing treatments, or dealing with a naturally compromised immune system, these tips can help strengthen your defenses and navigate daily life more effectively.
Maintain Good Hygiene and a Safe Environment
This involves washing hands regularly and keeping living spaces clean to reduce exposure to bacteria and viruses. Additionally, wearing a mask in large gatherings may be appropriate depending on the season and avoiding being in contact with individuals who may be feeling ill.
Get Adequate Sleep
It has been shown that poor sleep quality increases risk of infections. Individuals with weakened immune systems should aim for 7–9 hours of quality sleep nightly. Establish a bedtime routine, create a comfortable sleeping environment, and limit screen time to 1–2 hours before bed.
Stay Up to Date on Vaccinations Recommended by Your Healthcare Team
Vaccines can provide additional protection against preventable diseases and help strengthen your immune response. This is very important for Individuals who have been treated with biologic medications. Certain vaccines may need to be timed in accordance with biologic medication. Please seek the input of your healthcare teams to help coordinate the timing of a vaccine.
Manage Stress Levels
There has been an association with high levels of chronic stress and the ineffectiveness of the immune system. Although stressors are an expected occurrence in life, individuals should learn to manage them well. Incorporate stress-reducing activities such as meditation, deep breathing, yoga, or enjoyable hobbies into your routine. Furthermore, exercise has been proven to reduce stress levels and boost immune system function. It is recommended to do at least 3–5 days of 30 minutes of aerobic exercise per week.
Prioritize Nutrition
A balanced diet is crucial. Focus on fruits, vegetables, whole grains, and lean proteins. Proper hydration supports overall health. Drink an adequate amount of water and include hydrating foods like fruits and vegetables in your diet.
Living with a weakened immune system requires a proactive approach to health. Prioritize overall wellness and be proactive about hygiene, maintaining a safe environment and following vaccination recommendations. Small lifestyle changes can have a significant impact, empowering you to live a fulfilling life despite the challenges of having a weakened immune system.